Approach to paraneoplastic hyperhidrosis in palliative care: a literature review

Authors

Sandra Ribeiro USF Aníbal Cunha - ACeS Porto Ocidental, Porto https://orcid.org/0000-0002-8489-1546
Sara Inês Pinto Sousa USF São João de Ovar - ACeS Baixo Vouga, Ovar https://orcid.org/0009-0005-3044-4440
Sara Alexandra Moutinho Ferreira Serviço de Cuidados Paliativos - Instituto Português Oncologia do Porto Francisco Gentil, Porto https://orcid.org/0000-0002-4000-6226
Michael Sapateiro Luis Serviço de Cuidados Paliativos – Instituto Português de Oncologia do Porto Francisco Gentil, Porto https://orcid.org/0000-0002-6625-5183

DOI:

https://doi.org/10.31877/on.2023.47.01

Keywords:

Sweating, Hyperhidrosis, Palliative Care, Palliative Medicine, Hospice Care

Abstract

Introduction: This article reviews the current scientific evidence on the approach to paraneoplastic hyperhidrosis in patients receiving palliative care.

Methods: Our search was conducted in MEDLINE/Pubmed®, Cochrane, DARE®, BMJ EBM®, NICE®, CMAJ® and Bandolier, using the MeSH terms “Sweating”, “Hyperhidrosis”, “Palliative Care”, and “Palliative Medicine”. We used the Oxford scale to assess the quality of the included studies.

Results: This review includes 13 articles on the therapeutic approach to paraneoplastic hyperhidrosis using the following interventions: thioridazine, thalidomide, olanzapine, gabapentin, cannabinoids, acupuncture and Chinese herbal medicine. We obtained heterogeneous results and, while these interventions are in general beneficial for controlling paraneoplastic hyperhidrosis in palliative care, no robust evidence exists that unequivocally demonstrates one approach is more beneficial than another.

Conclusions: At present, the available evidence on the therapeutic approach to paraneoplastic hyperhidrosis in palliative care has low quality (Level of Evidence 4; Strength of Recommendation C).

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Published

2023-10-26

How to Cite

Ribeiro S, Pinto Sousa SI, Moutinho Ferreira SA, Sapateiro Luis M. Approach to paraneoplastic hyperhidrosis in palliative care: a literature review. Onco.News [Internet]. 2023 Oct. 26 [cited 2024 Dec. 18];(47):e0166 . Available from: https://onco.news/index.php/journal/article/view/166