Use and management of Trastuzumab Deruxtecan in people with breast cancer: recommendations
DOI:
https://doi.org/10.31877/on.2024.49.05Keywords:
Trastuzumab deruxtecan, Breast, Cancer, Recommendation, NursesAbstract
Trastuzumab Deruxtecan is indicated for the treatment of Human Epidermal growth factor Receptor-type 2 HER2-positive or HER2-low breast cancer, showing favorable efficacy and safety profiles. However, it can lead to some severe adverse events, such as interstitial lung disease.
We performed four regional experience sharing sessions and one final national discussion session, with the participation of several nurses from different Portuguese hospitals and two “Associação de Enfermagem Oncológica Portuguesa” representatives. The purpose of this document is to develop broad national recommendations for nurse practice, to standardize the administration and management of adverse events related to Trastuzumab Deruxtecan.
It is essential to raise awareness among patients to report any signs and symptoms during treatment with Trastuzumab Deruxtecan. Immediate action with the recommendations herein may avoid complications that lead to drug discontinuation and/or serious outcomes.
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Copyright (c) 2024 Ana Paula Amorim, Ana Raquel Chemela, Rita Cordeiro, Jorge Freitas, Carlos Góis, Bárbara Lamas, Vanesa Núñez, Susana Pedro, Sandra Ponte
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