Intervenções de enfermagem à pessoa com risco de tromboembolismo venoso associado à quimioterapia: Scoping Review

português

Autores

DOI:

https://doi.org/10.31877/on.2024.50.04%20

Palavras-chave:

Cancro, Cuidados de enfermagem, Prevenção primária e secundária, Quimioterapia, Tromboembolismo venoso

Resumo

Introdução: O tromboembolismo venoso é a segunda causa de morte na pessoa com cancro. Este risco aumenta em pessoas sob quimioterapia. Esta complicação provoca sofrimento físico e emocional, sendo fundamental intervenções de enfermagem dirigidas. Objetivo: Mapear a evidência científica sobre intervenções de enfermagem que permitem prevenir e gerir o tromboembolismo venoso na pessoa com doença oncológica sob quimioterapia. Métodos: Scoping Review segundo metodologia do Instituto Joanna Briggs. Pesquisa realizada nas bases de dados MEDLINE® e CINAHL® em abril de 2023. A revisão seguiu a checklist PRISMA-ScR EQUATOR.
Resultados: Incluídos 26 artigos, publicados entre 2004 e 2023. Após análise, emergiram três grandes dimensões: avaliação do risco de tromboembolismo venoso, intervenções autónomas e intervenções interdependentes. Conclusão: O enfermeiro é preponderante na prevenção e gestão do tromboembolismo venoso, recorrendo a uma abordagem sistematizada de avaliação do risco, educação e vigilância de sinais e/ou sintomas destas complicações e implementação de intervenções dirigidas.

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Referências

Direção-Geral da Saúde. Programa nacional para as doenças oncológicas 2017 [Internet]. 2017 [citado 25 de Abril de 2023]. Available at: https://comum.rcaap.pt/bitstream/10400.26/22531/1/Programa%20Nacional%20para%20as%20Doen%C3%A7as%20Oncol%C3%B3gicas%202017.pdf

Khorana A. Cancer and thrombosis: implications of published guidelines for clinical practice. Annals of Oncology. 2009;20(10):1619–30. https://doi.org/10.1093/annonc/mdp068

Mulder F, Horváth-Puhó E, Es N, Laarhoven H, Pedersen L, Moik F, et al. Venous thromboembolism in cancer patients: a population-based cohort study. Blood.2021;137(14):1959–69. https://doi.org/10.1182/blood.2020007338

Navi B, Reiner A, Kamel H, Iadecola C, Okin P, Elkind M, et al. Risk of arterial thromboembolism in patients with cancer. J Am Coll Cardiol. 2017;70(8):926–38. https://doi.org/10.1016/j.jacc.2017.06.047

Mahajan A, Brunson A, Adesina O, Keegan T, Wun T. The incidence of cancer-associated thrombosis is increasing over time. Blood Adv. 2022;6(1):307–20. https://doi.org/10.1182/bloodadvances.2021005590

Donnellan E, Khorana A. Cancer and venous thromboembolic disease: A review. Oncologist. 2017;22(2):199–207. https://doi.org/10.1634/theoncologist.2016-0214

Falanga A, Ay C, Di Nisio M, Gerotziafas G, Jara-Palomares L, Langer F, et al. Venous thromboembolism in cancer patients: ESMO clinical practice guideline. Annals of Oncology.2023;34(5):452–67. https://doi.org/10.1016/j.annonc.2022.12.014

Renni M, Cerqueira M, Trugilho I, Junior M, Marques M, Koch H. Mecanismos do tromboembolismo venoso no câncer: uma revisão da literatura. J Vasc Bras. 2017;16(4):308–13. https://doi.org/10.1590/1677-5449.007817

Khorana A, Francis C, Culakova E, Kuderer N, Lyman G. Frequency, risk factors, and trends for venous thromboembolism among hospitalized cancer patients. Cancer.2007;110(10):2339–46. https://doi.org/10.1002/cncr.23062

Grover S, Hisada Y, Kasthuri R, Reeves B, Mackman N. Cancer therapy-associated thrombosis. Arterioscler Thromb Vasc Biol. 2021;41(4):1291–305. https://doi.org/10.1161/atvbaha.120.314378

Baddeley E, Torrens‐Burton A, Newman A, Nelson A, Pease N, Nelson R, et al. A mixed‐methods study to evaluate a patient‐designed tool to reduce harm from cancer‐associated thrombosis: The EMPOWER study. Res Pract Thromb Haemost. 2021;5(5):1–12. https://doi.org/10.1002/rth2.12545

Rossel A, Robert-Ebadi H, Marti C. Preventing venous thromboembolism in ambulatory patients with cancer: A Narrative Review. Cancers (Basel). 2020;12(3):1–14. https://doi.org/10.3390/cancers12030612

Streiff M, Holmstrom B, Angelini D, Ashrani A, Elshoury A, Fanikos J, et al. Cancer-associated venous thromboembolic disease, version 2.2021, NCCN clinical practice guidelines in oncology. J Natl Compr Canc Netw. 2021;19(10):1181–201. http://www.ncbi.nlm.nih.gov/pubmed/34666313

Bayadinova J, Sardo L, Higgins-Nogareda V, Scott J, MacKinnon B. «Spot the CLOT»: What cancer patients want to know. Canadian Oncology Nursing Journal. 2022;32(1):145–50. http://www.ncbi.nlm.nih.gov/pubmed/35280058

Noble S, Prout H, Nelson A. Patients’ experiences of living with cancer-associated thrombosis: the PELICAN study. Patient Prefer Adherence. 2015; 9:337–45. https://doi.org/10.2147/PPA.S79373

Ordem dos Enfermeiros. Regulamento no613/2022 que define o ato do enfermeiro. Diário da República, 2nd serie [internet]. 2022 [cited 25th April, 2023]; Part E (131): 179-82. Available at: https://www.ordemenfermeiros.pt/media/26674/regulamento-ato-do-enfermeiro.pdf

Morrison R. Venous thromboembolism: Scope of the problem and the nurse’s role in risk assessment and prevention. Journal of Vascular Nursing. 2006;24(3):82–90. https://doi.org/10.1016/j.jvn.2006.05.002

Holmes C, Ades S, Gilchrist S, Douce D, Libby K, Rogala B, et al. Successful model for guideline implementation to prevent cancer-associated thrombosis: venous thromboembolism prevention in the ambulatory cancer clinic. JCO Oncol Pract. 2020;16(9):e868–74. https://doi.org/10.1200/JOP.19.00697

Peters M, Godfrey C, McInerney P, Munn Z, Tricco A, Khalil H. Chapter 11: Scoping reviews. Em: Aromataris E, Munn Z, editores. JBI Manual for Evidence Synthesis. The Joanna Briggs Institute; 2020. https://doi.org/10.46658/JBIRM-19-01

Tricco A, Lillie E, Zarin W, O’Brien K, Colquhoun H, Levac D, et al. PRISMA Extension for Scoping Reviews (PRISMA-ScR): Checklist and explanation. Ann Intern Med. 2018;169(7):467–73. https://doi.org/10.7326/M18-0850

World Health Organization. Older adolescent (15 to 19 years) and young adult (20 to 24 years) mortality [Internet]. World Health Organization;2022 [citado 4 de Março de 2024]. Disponível em: https://www.who.int/news-room/fact-sheets/detail/levels-and-trends-in-older-adolescent-%2815-to-19-years%29-and-young-adult-%2820-to-24-years%29-mortality

Bulechek G, Butcher H, Dochterman J. Classificação das intervenções de enfermagem (NIC). 5a. Guedes R, editor. Rio de Janeiro: Elsevier Editora Ltda.; 2010. 1–1037 p.

American Society of Clinical Oncology (ASCO). How Chemotherapy Drugs Work [Internet]. American Cancer Society, Inc. 2019 [Cited 2nd April, 2023]. Available at: https://www.cancer.org/cancer/managing-cancer/treatment-types/chemotherapy/how-chemotherapy-drugs-work.html

Page M, Moher D, Bossuyt P, Boutron I, Hoffmann T, Mulrow C, et al. PRISMA 2020 explanation and elaboration: updated guidance and exemplars for reporting systematic reviews. BMJ. 2021;373(160). https://doi.org/10.1136/bmj.n160

Spyropoulos A, Eldredge J, Anand L, Zhang M, Qiu M, Nourabadi S, et al. External validation of a venous thromboembolic risk score for cancer outpatients with solid tumors: The COMPASS-CAT venous thromboembolism risk assessment model. Oncologist. 2020;25(7): e1083–90. https://doi.org/10.1634/theoncologist.2019-0482

Viale PH. Abnormal clotting in cancer: An overview of pathophysiology and etiology. Semin Oncol Nurs. 2005;21(4):12–20. https://doi.org/10.1016/j.soncn.2005.10.013

Viale P, Schwartz R. Venous thromboembolism in patients with cancer part I: Survey of oncology nurses’ attitudes and treatment practices for ambulatory settings. Clin J Oncol Nurs. 2004;8(5):455–61. DOI:10.1188/04.CJON.455-461

Khorana A, Rao M. Approaches to risk-stratifying cancer patients for venous thromboembolism. Thromb Res. 2007;120(2):S41–50. https://doi.org/10.1016/S0049-3848(07)70129-9

Kuderer N, Lyman G. Guidelines for treatment and prevention of venous thromboembolism among patients with cancer. Thromb Res. 2014;133: S122–7. https://doi.org/10.1016/S0049-3848(14)50021-7

Dutia M, White RH, Wun T. Risk assessment models for cancer‐associated venous thromboembolism. Cancer. 2012;118(14):3468–76. https://doi.org/10.1002/cncr.26597

Angelini D, Khorana A. Risk assessment scores for cancer-associated venous thromboembolic disease. Semin Thromb Hemost. 2017;43(05):469–78. https://doi.org/10.1055/s-0036-1597281

Ashrani A, Gullerud R, Petterson T, Marks R, Bailey K, Heit J. Risk factors for incident venous thromboembolism in active cancer patients: A population based case–control study. Thromb Res. 2016; 139:29–37. https://doi.org/10.1016/j.thromres.2016.01.002

Cunningham R. The role of low-molecular-weight heparins as supportive care therapy in cancer-associated thrombosis. Semin Oncol. 2006;33(4):17–25. https://doi.org/10.1053/j.seminoncol.2006.01.022

Lyman G, Bohlke K, Khorana A, Kuderer N, Lee A, Arcelus J, et al. Venous thromboembolism prophylaxis and treatment in patients with cancer: american society of clinical oncology clinical practice guideline update 2014. Journal of Clinical Oncology. 2015;33(6):654–6. https://doi.org/10.1200/JCO.2014.59.7351

Key N, Khorana A, Kuderer N, Bohlke K, Lee A, Arcelus J, et al. Venous thromboembolism prophylaxis and treatment in patients with cancer: ASCO guideline update. Journal of Clinical Oncology. 2023;41(16):3063–71. https://doi.org/10.1200/JCO.23.00294

Sardo L, Bayadinova J, Jenkins S, Penton L. The significance of VTE in cancer: Introduction of the «Spot the Clot» series. Canadian oncology nursing journal. 2021;31(4):500–3. Disponível em: http://www.ncbi.nlm.nih.gov/pubmed/34786471

Bayadinova J, Sardo L, Penton L, Jenkins S. «Spot the CLOT»: Awareness of cancer-associated thrombosis in healthcare providers. Canadian Oncology Nursing Journal. 2022; 32(2):325–30. Disponível em: https://europepmc.org/article/MED/35582246

Nisio M, van Es, Rotunno L, Anzoletti N, Falcone L, Tursi M, et al. Long-term performance of risk scores for venous thromboembolism in ambulatory cancer patients. J Thromb Thrombolysis. 2019;48(1):125–33. https://doi.org/10.1007/s11239-019-01845-6

Fu J, Cai W, Zeng B, He L, Bao L, Lin Z, et al. Development and validation of a predictive model for peripherally inserted central catheter-related thrombosis in breast cancer patients based on artificial neural network: A prospective cohort study. Int J Nurs Stud. 2022; 135:1–8. https://doi.org/10.1016/j.ijnurstu.2022.104341

Kirschner M, Hartmann N, Parmentier S, Hart C, Henze L, Bisping G, et al. Primary thromboprophylaxis in patients with malignancies: Daily practice recommendations by the hemostasis working party of the German Society of Hematology and Medical Oncology (DGHO), the Society of Thrombosis and Hemostasis Research (GTH), and the Austrian Society of Hematology and Oncology (ÖGHO). Cancers (Basel). 2021;13(12):1–27. https://doi.org/10.3390/cancers13122905

Syrigos K, Grapsa D, Sangare R, Evmorfiadis I, Larsen A, Van Dreden P, et al. Prospective assessment of clinical risk factors and biomarkers of hypercoagulability for the identification of patients with lung adenocarcinoma at risk for cancer-associated thrombosis: The observational ROADMAP-CAT Study. Oncologist. 2018;23(11):1372–81. https://doi.org/10.1634/theoncologist.2017-0530

Farge D, Bosquet L, Kassab-Chahmi D, Mismetti P, Elalamy I, Meyer G, et al. 2008 french national guidelines for the treatment of venous thromboembolism in patients with cancer: Report from the working group. Crit Rev Oncol Hematol. Janeiro de 2010;73(1):31–46. https://doi.org/10.3390/cancers12030618

Hilário T, Mantovani V, Aliti G, Lucena A, Rabelo-Silva E. Trombose: análise de conceito como subsídio teórico para qualificar a prática clínica de enfermeiros. Online Brazilian Journal of Nursing. 2022; 21:1–11. https://doi.org/10.17665/1676-4285.20226580

Lyman G, Carrier M, Ay C, Nisio M, Hicks L, Khorana A, et al. American Society of Hematology 2021 guidelines for management of venous thromboembolism: prevention and treatment in patients with cancer. Blood Adv. 2021;5(4):927–74. https://doi.org/10.1182/bloodadvances.2020003442

Dias I, Marins A, Franco A, Carvalho E, Souza N, Andrade K. Avaliação de risco para tromboembolismo venoso: estudo bibliométrico para a prática clínica de cardioncologia. Revista Enfermagem Atual In Derme. 2022;96(39):1–16. https://doi.org/10.31011/reaid-2022-v.96-n.39-art.1438

Overvad T, Ording A, Nielsen P, Skjøth F, Albertsen I, Noble S, et al. Validation of the Khorana score for predicting venous thromboembolism in 40 218 patients with cancer initiating chemotherapy. Blood Adv. 2022;6(10):2967–76. https://doi.org/10.1182/bloodadvances.2021006484

Haggstrom L, Parmar G, Brungs D. Central venous catheter thrombosis in cancer: A Multi-centre retrospective study investigating risk factors and contemporary trends in management. Clin Med Insights Oncol. 2020;14:1–6. https://doi.org/10.1177/1179554920953097

Falanga A, Russo L, Milesi V, Vignoli A. Mechanisms and risk factors of thrombosis in cancer. Crit Rev Oncol Hematol. 2017; 118:79–83. https://doi.org/10.1016/j.critrevonc.2017.08.003

Riegel B, Jaarsma T, Strömberg A. A Middle-Range Theory of Self-Care of Chronic Illness. Advances in Nursing Science. 2012;35(3):194–204. DOI: 10.1097/ANS.0b013e318261b1ba

Liz-Pimenta J, Tavares V, Neto B, Santos J, Guedes C, Araújo A, et al. Thrombosis and cachexia in cancer: Two partners in crime? Crit Rev Oncol Hematol. 2023; 186:1–15. https://doi.org/10.1016/j.critrevonc.2023.103989

Silva S, Santos J, Silva M, Costa R, Medeiros R. Cancer cachexia and its pathophysiology: links with sarcopenia, anorexia and asthenia. J Cachexia Sarcopenia Muscle. 2020;11(3):619–35. https://doi.org/10.1002/jcsm.12528

Potere N, Barco S, Mahé I, Cesarman-Maus G, Angchaisuksiri P, Leader A, et al. Awareness of venous thromboembolism among patients with cancer: Preliminary findings from a global initiative for World Thrombosis Day. J Thromb Haemost. 2022;20(12):2964–71. https://doi.org/10.1111/jth.15902

Vidigal P, Garcia T, Santos M, Camacho A, Souto M, Borges G, et al. Subconjunto terminológico CIPE® para pacientes com tromboembolismo venoso associado a câncer. Acta Paulista de Enfermagem. 2018;31(4):382–90. https://doi.org/10.1590/1982-0194201800054

Xu L, Fu C, Zhang Q, He C, Wei Q. The effectiveness of exercise training in treating venous thromboembolism: a systematic review. Vol. 49, Physician and Sportsmedicine. Taylor and Francis Ltd.; 2020. p. 1–11. https://doi.org/10.1080/00913847.2020.1786746

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12-03-2025

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Marcelino AI, Martins PM, Frade AI, Miguel SSA, Santos da Costa MA. Intervenções de enfermagem à pessoa com risco de tromboembolismo venoso associado à quimioterapia: Scoping Review: português. Onco.News [Internet]. 12 de Março de 2025 [citado 23 de Março de 2025];(50):e0282. Disponível em: https://onco.news/index.php/journal/article/view/282

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